The Long String STAR V
EXPANDING THE FIELD OF VIEW THROUGH INNOVATION
In this ever-evolving field, new innovations continue to shed light on this uncharted territory and drive new discoveries. Bionano has developed Optical Genome Mapping (OGM), a technique that trans- forms the view of the genome, by detecting struc- tural variants in an unbiased, genome-wide fashion. In contrast to conventional sequencing techniques, OGM leverages the extraction and labeling of Ultra High Molecular Weight (UHMW) DNA. Thanks to Hamilton’s focus and long-standing expertise in automating genomic workflows, we are now stepping into the most advanced applica- tion areas. With the Long String STAR V for UHMW DNA extraction and labeling, we are now proudly presenting the world’s first automation solution for these processes. In conjunction with OGM, you will be able to see what has been hidden for so long. Take the next step towards answering open questions in genomic analysis, while working efficiently and at scale.
PIONEERING TOWARDS BETTER RESOLUTION OF STRUCTURAL VARIATION
Over the past few decades, the understanding of biological principles and processes has evolved tremendously. An invaluable contribution towards this gain in knowledge is attributable to advances in genomic research and technologies. Next-Generation Sequencing (NGS) approaches, as well as other techniques, have had a fundamen- tal impact on life sciences and many applied fields within our society. But the journey is far from over. Although well established, current NGS methods are unable to accurately resolve certain regions of the genome. This makes the detection of structural variants particularly challenging. Different cyto- genetic techniques have their own limitations as well. Even in concert, these methods cannot pro- vide a complete and high-resolution picture of the genome. This inability represents one of the last frontiers in genomics.
Conventional DNA Extraction Short-Read Sequencing Data 150 bp / Molecule
UHMW DNA Extraction * Optical Genome Mapping Data ≥ 230,000 bp / Molecule
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Throughout this brochure, protected product names may be used without being specifically marked as such.
*The DNA isolated from the Hamilton Long String STAR V contains Mbp length molecules which overall exceed the OGM quality threshold of 230 kbp post extraction, labeling, linearization, and imaging.
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