Hamilton Long String STAR V™ Brochure

Long String Genomics

New Frontiers

OPTICAL GENOME MAPPING - THE FUTURE IS NOW

MOVING FORWARD BY CLOSING GAPS

Use UHMW DNA to perform OGM for unbiased, genome-wide detection of structural variants across a broad range of research applications:

An alternative to traditional cytogenetic workflows to detect more chromosomal aberrations in a sin- gle assay OGM detects the structural variants that are missed by sequencing with higher resolution than traditional cytogenetic methods. Reset the benchmark for detecting chromosomal aberrations.

Using the Long String STAR V in your laboratory will provide you with the opportunity to extract and label UHMW DNA easier than ever before with sample throughput surpassing manual capabilities. Get the power to bring your workflow performance to the next level. Human handling errors are a thing of the past, and the user-to-user variation seen with manual protocols is replaced by automated consistency and reproducibility. The Long String STAR V from Hamilton and OGM solutions from Bionano add another layer of discovery to your genetic experiments. With the ability to reliably extract and label ultra-long DNA molecules paired with the Bionano Saphyr system, all classes of structural variants are revealed and short-read sequencing blindspots can be unveiled. Together, Long String STAR V and OGM deliver a view that empowers you to overcome challenges and discover more.

Constitutional genetic disorders

Hematologic malignancies

Solid tumors

Cell bioprocessing quality control Gene discovery and therapy Reference genome assembly

Complement data across the variant continuum by combining OGM with NGS-based methods

By combining OGM and NGS, you can characterize both structural and single nucleotide variants, providing a comprehensive analysis of genomic variation that can impact human health. Reveal more that matters for powerful genetic discovery.

You have just turned from page 3 to page 12 and the OGM Data / molecule has covered all pages, while conventional NGS Data has taken only a very small space on page 3.

For more information about potential applications for Optical Genome Mapping with UHMW DNA, visit bionanogenomics.com.

* The DNA isolated from the Hamilton Long String STAR V contains Mbp length molecules which overall exceed the OGM quality threshold of 230 kbp post-extraction, labeling, linearization, and imaging.

Yes, that long!

UHMW DNA Extraction * Optical Genome Mapping Data ≥ 230,000 bp / Molecule