Multifunctionality transforming problems into solutions
Microlab ® STAR TM Multifunctionality transforming problems into solutions
Contents
The New STAR
AS GOOD AS EVER – ONLY BETTER
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At a glance
Usability Software
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Multifunctionality
Come to stay. The Microlab STAR has always been used in a wide variety of laboratories, universities and institutions. While its design is a testament to excellent engineering, the standout feature of the STAR is flexibility. A variety of features and configuration options ensure that every customer's needs are met. It can be expanded, specialized and individualized. Over the years, the benefits have transformed with the introduction of new modules, carriers, and integrations. The Microlab STAR is constantly developing while increasing its value for users in Life Sciences and Diagnostics. The debut of the new Microlab STAR has achieved another milestone for Hamilton. Practicality, stronger safety measures, and precision make it easy for it to be the STAR in any workplace setting.
Hardware Modularity
Safety Process
Production
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Specifications
About
Throughout this brochure, protected product names may be used without being specifically marked as such.
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The STAR IN YOUR LAB
Your Lab Becomes SMARTER
Tailored to the specific needs of laboratories in Life Sciences and Diagnostics, the Microlab STAR is the ideal companion for the challenges of the future. It can be altered or upgraded throughout its lifespan to accommodate changing lab workflows. The holistic design seamlessly integrates innovative functions, safety, robustness and ease of use, in a minimalistic and transparent appearance. The robotic platform has been updated with current electronics to ensure a smoother workflow in the lab.
VENUS software Power Steps have been further improved to make programming of routine automation steps more intuitive and efficient. In addition, the new CO-RE II technology makes the pipetting tip positioning even more reliable while simultaneously reducing cost due to reduced service needs.
Let the centerpiece of your laboratory become an eye catcher. The Microlab STAR not only looks smart, it creates order and provides a sense of awareness in the laboratory. With the multifunctional status light, you can instantly recognize the process status of the STAR, even from a distance. Additionally, the switchable interior light ensures perfect lighting conditions on the deck - adding increased convenience during visual monitoring and user safety during manual intervention when preparing or cleaning the deck.
But it's not just the smart illumination concept that makes your Microlab STAR more convenient - the functional design also protects the operator. Access to the waste bags is now even easier and safer, as the operator is no longer exposed to chemicals and samples, preventing contamination.
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Status LIGHT
Interior LIGHT
ENLIGHTEN YOUR DECK - RECOGNIZE ANY DETAIL
Status information at a glance Different colors & different lengths Indicates progress of run At the front of the instrument
No need to come to the instrument No need to activate the screen of the PC
Improved process safety
Add optional status light tower
Microlab STAR
Ready to Use
Microlab STAR
Illumination of the deck
Runs Independently
Better view of deck components
Microlab STAR
User Action Required
Microlab STAR
Intuitive activation
Error Pending
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Software VENUS five
POWER STEPS – SIMPLIFY YOUR WORKFLOW
Color codes immediately indicate which tip type is used to aspirate from which source and into which target.
BETTER USER GUIDANCE AND PROGRAMMING
The new VENUS five software provides basic and advanced programming, offering flexible assay setup without compromising your requirements. Intuitive editors provide full control over every aspect of your method. VENUS five is designed to be as easy as you need, yet powerful enough to provide the flexibility to set up assays exactly the way you want them automated.
The most important parameters can be seen at a glance, and the volume, liquid and additional handling of the tips (waste/reuse) can be adjusted simply and easily.
Power Steps
VENUS' Power Steps offer a quick and easy start into the world of automation, for everyone, and at any time. There are five intuitive visual guides for the most frequently used pipetting tasks:
Transfer Samples
Replicates Hit Picking
Add Reagent Serial Dilution
Here, the most common reasons for errors can be controlled so that no valuable time is lost, and the workflow runs as smoothly as possible without user interaction.
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State of the ART
HAMILTON PIPETTING TECHNOLOGIES
For decades, Hamilton has defined the standard for high-precision liquid handling. Quality engineering, unique innovation, and outstanding service and support contribute to precise performance and overcoming liquid challenges. The introduction of CO-RE II technology has also created additional customer benefits. Combining the patented CO-RE II technology with intelligent software, the Microlab STAR ensures the most reliable and safe liquid handling performance, assuring trustworthy results while lowering costs in laboratory routines.
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Intelligent PIPETTING
WITH A TEAM OF TECHNOLOGIES
Liquids in the tip, not on the tip: Dual Liquid Level Detection (Dual LLD)
Aspirates with proof: Monitored Air Displacement (MAD)
Pipettes with proof: Total Aspiration and Dispense Monitoring (TADM)
In the lab, technology and precision are essential in guaranteeing maximum process reliability and to safeguard samples. The smooth interplay between software and mechatronics, coupled with an intuitive user interface makes the liquid handling of the Microlab STAR easy to program and less error prone.
Liquid Level Detection (LLD) determines liquid levels in tubes and plates located on the pipetting deck in two modes: capacitive LLD (cLLD) to detect conductive liquids; and pressure-based LLD (pLLD), to detect virtually all liquid types, including foaming liquids and non-conductive organic solvents. No matter what characteristics your liquids have, the Microlab STAR makes sure they’re safely pipetted.
Monitored Air Displacement (MAD) detects clots or empty wells with real-time tracking of aspiration performance, and it can also be used to pipette highly volatile solvents.
Total Aspiration and Dispense Monitoring (TADM) offers real-time monitoring of each independent pipetting channel during aspiration and dispensing and verifies sample transfer with a traceable digital audit trail.
Even better tip attachment and precision: New CO-RE II technology
Aspiration
Dispense
The innovative design with its new stop disk and improved CO-RE II tip design offers unique value to the automation community in Life Sciences and Diagnostics. Up to 15x life span Less wear and tear Higher precision pipette tip alignment Simplified serviceability and reduced preventative maintenance leads to lower total cost of ownership
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Handles difficult liquids accurately: Anti-Droplet Control (ADC)
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Anti-Droplet Control (ADC) detects and reacts to real- time pressure changes from volatile organic solvents in each pipetting channel to prevent inadvertent dripping.
Ambient- Pressure
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Normal
Empty
Clogged
A
B
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Time
Plunger
1 Blocked Tip, Blood Clot 2 Short Sample / No Sample 3 Incorrect Volume 4 Short Sample
1 Dispense Speed Incorrect / Blocked Tip 2 Leaky System / Lost Sample 3 Incorrect Volume
Channel
Pressure Sensor
Time
C
Metal Coupling
Tip
CO-RE II sealing surface
Volatile Liquid
Time
CO-RE II
A Schematic sketch showing a pipetting channel with its pressure sensor. The volatile liquid contained in the tip evaporates into the air space. B Pipetting without ADC, as the pressure in the tip increases, a droplet forms at the end of the tip, reducing the pressure in the tip when it falls off. C Pipetting with ADC, pressure differences are detected by the pressure sensor and will be compensated in real-time by plunger movements: droplet formation is prevented.
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PLATFORMS
Housing EXTENSION
MODULARITY & FLEXIBILITY
EXTRA SAFETY OPTIONS: KEEP GERMS OUT
Robot-specific needs are just as individual as their users. This dynamic is reflected by the modularity of the Microlab STAR Line - with the ideal configuration for your business.
Depending on the instrument configuration, several housing extensions support the convenience of working with the instrument: Slim left side Slim right side Wide left side (for use with Multi-Probe Heads)
Additional housing options include UV Kit for easy system disinfection and STAR CAP (Clean Air Protection) that turns any Microlab STAR into a laminar flow hood.
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Standard CARRIERS
Multiflex MODULES
Multiflex MTP Modul For any type of microplates
Tip Carrier Holds up to five racks of tips
Sky Frame With the Sky Frame,
Carriers are the base of any workflow. There are various parameters that need to be considered: Capacity, type of consumables, samples, etc. Maintaining flexibility is also important. The ability to adapt is also important to workflow success. In addition to the standard carriers with five identical positions, the Multiflex concept allows you to configure the positions individually.
framed racks with filter tips can be stacked on top of each other. This doubles the capacity of the filter tips without losing valuable deck space.
Plate Carrier For a wide range of plate types
Tube Carrier Holds tubes up to 18 mm in diameter
Reagent Carrier For reagent troughs
Multiflex Tube/Cup Module Holds different types of tubes
Stacking Carrier Increase deck capacity by stacking up to ten plates
Multiflex Stacker Module For Stacking up to 10 microplates
Multiflex Active Plate Nest For exact positioning and fixing of microplates
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Functional MODULES
THERE'S NO LIMIT
Flexibility thanks to modularity: The Microlab STAR is a platform that can be easily adapted to the needs of the future. A wide range of standard carriers can be used to adapt the system deck to your requirements. Functional modules can be added to achieve an even higher degree of automation, so that every need within the workflow is taken into consideration. From heating to shaking, to cooling and much more. The expandable modules create added value for every workflow in every laboratory, and also maximize walk-away time. Here you can see a small selection - more modules can be found on our website.
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The Hamilton Heater Shaker
The Liquid Dispenser
The Hamilton Heater Shaker (HHS) automates the heating and shaking of ANSI/SLAS footprint microplates. Multiple units may be integrated and connected via a control box for higher throughput applications.
The Liquid Dispenser works in two directions. On one hand, it can be used as a dispenser for larger quantities of liquid without losing valuable deck space. Alternatively, it can be used as a liquid waste by aspirating liquid that is no longer needed from the deck.
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The Hamilton Heater Cooler
The Cooling Carrier Module
The Hamilton Heater Cooler (HHC) offers wide-ranging and precise temperature control for ANSI/SLAS footprint microplates.
The Cooling Carrier Module combines two essential features: Cool samples to a predefined temperature Identify barcodes via Autoload
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Pipetting TOOLS
CO-RE TOOLS
MORE THAN JUST LIQUID HANDLING Combined with our CO-RE tools, the pipetting channels allow a variety of functions such as transport and handling of different labware. This multifunctionality not only ensures a more efficient workflow, but also enormously expands the automation options and optimizes the capacity of the labware. The iSWAP robotic plate handler compliments these tools and enables off-deck integration of third- party devices.
CO-RE Gripper
The CO-RE Gripper is a plate handling tool, picked up by two pipetting channels during a run. It can transport different labware such as microplates, lids of microplates, archive- and filter plates.
FlipTube Tool
Hamilton FlipTubes are 1.5 ml reagent tubes with a lid attached that closes the tube tightly for reliable preparation, centrifugation and storage of small volume samples. The FlipTube Tool allows for automated fast opening and closing without risk of human interaction and contamination risk.
Individual Channels
Multi-Probe Heads
Suction Tool
The 1000 µL pipetting channels offer a volume range from 1.0 µL up to 1000 µL, while the 5 ml Pipetting Channel covers a volume range of 50 µL to 5000 µL. Both Channel Types allow independent movement with asymmetric spreading. Both combinations allow unrivaled dynamic range for your assays. The unique tip design of the 5 ml channel allows you to use small tubes and plates in your application while still pipetting large volumes, therefore maximizing the instrument’s flexibility.
Our CO-RE 96- and 384-Multi-Probe Heads (MPH) allow for the quick pipetting of entire 96 or 384-well plates, or partial plates. Liquid Level Detection ensures reliable liquid handling.
The Suction Tool is a device for picking up and transporting lightweight lids of petri dishes, plates, troughs, reservoirs, and even FlipTubes.
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Applications
There are no limits to your imagination
Genomics Cellomics Diagnostics Forensics
We created the tool, but the possibilities are endless. Our technology supports you in realizing your vision and attaining your goals through customized solutions and a spectrum of features - no matter what application.
Proteomics Biobanking Drug Discovery Industrial Biotech
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Focus: SAFETY
WHEN SAFETY MATTERS
Safety is the core topic in any laboratory; it needs to be considered for users, samples and processes, and your investments. To guarantee a safe process for both you and your samples, we’ve built-in a number of safety features to give you maximum confidence that processes are performed correctly while maximizing the reliability of generated results: Racksare identifiedand loadedautomatically, barcodes of samples are tracked, and all pipetting tasks are meticulously recorded. Losing samples is never an option - sophisticated error handling strategies allow assays to run uninterrupted in most scenarios, by offering a clear indication whenever user interaction is needed.
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Safe PROCESS
AUTOLOAD
THE SAMPLE IN FOCUS
INTELLIGENT PIPETTING
WORKLIST HANDLING
Without process reliability the entire workflow is at risk – because errors can happen. We do everything to ensure those risks are mitigated. Using a variety of sophisticated technologies and solutions, we ensure that all your samples and processes are safeguarded from loading to analysis. This holistic approach guarantees security. The traceability throughout the entire workflow and optimal handling ensures accountability.
Worklist Handling Badge Number Tracking
2D BARCODE IDENTIFICATION
BADGE NUMBER TRACKING
Autoload with Tracking
SAMPLE
Customizable Error Recoveries Labware Reporting Intelligent Pipetting Bi-Directional LIMS Integration
Status Light
2D-Barcode Reading
STATUS LIGHT
LIMS
PROCESS REPORT
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STARwatch
A SYSTEM TO MONITOR YOUR STAR'S HEALTH
STARwatch is a service that significantly increases uptime of your instrument and is exclusively available for Microlab STAR instruments. Running behind the scenes, STARwatch continuously monitors the condition of your instrument. The data captured is automatically analyzed, and when critical patterns are recognized, Hamilton Service is immediately notified to provide proactive intervention. This ensures more planning and process reliability for you. Don't worry about technical details in the background - we do that for you. It's much more important that you can focus on your samples and results.
Unplanned Downtime
Increased system uptime through proactive intervention
Planned Service Time
No workflow interruption Pre-planned service visits Faster service reaction time
without STARwatch
with STARwatch
THE TECHNOLOGY BEHIND
STARwatchCollect is a small client, installedon the instrument’s computer, which transmits relevant information to the STARwatch Server. Encrypted and compressed data is only sent by a one-way SMTP protocol. Therefore, outside network access is not possible. When dealing with data transfers via the internet, security is a major concern.
With STARwatch Collect, data transfer is highly secure. Transmitted data is encrypted and compressed The update rate is configurable Safe “one way” connection using SMTP
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Safe INVESTMENT
SERVICE & SUPPORT AND HOW WE UNDERSTAND IT
Our worldwide service organization strives to provide the best service and support in the industry. Local field service engineers are trained by our Hamilton certified trainers and supported by service centers and distributors. Our commitment to high-quality standards goes beyond ISO 9001
certification, and includes continuous training of all authorized service technicians. With us as your automation partner, you can always rely on excellent service and support.
EXTRA-MILE SUPPORT
HIGHEST QUALITY LEVEL AND THE BEST SERVICE
Always there when you need us Our global field service and support network - from the technical support hotline to local service engineers and application specialists - guarantees fast response times to your inquiries in order to minimize possible downtimes. Whether it's routine maintenance, service or application support, we ensure that you can work as efficiently as possible. Training makes perfect We offer our trainings in the form of standard training sessions, as well as tailor-made to your individual needs - whether on our premises or in your lab.
Quality from a single source We guarantee the highest standards of quality, reliability and precision for all our products, from our own production and state-of-the-art quality control systems to final inspection. System installation made to measure All Hamilton systems are installed according to strict procedures and in accordance with ISO 9001. Each includes a comprehensive Installation Qualification (IQ) and detailed documentation. Service as individual as you are Ensure the longevity and peak performance of your automated system with a Hamilton service contract, including regular monitoring and preventative mainte- nance. There are three individual service and support contract levels to choose from.
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In-House PRODUCTION
Everything from a single source. Following this credo, almost all parts are manufactured in-house at Hamilton. As a result, we can react swiftly to developments and changes, complimenting our very high quality standards. In addition to CNC parts, we also produce our own tips and develop our own software. This enables us to react agilely in a market where quality and availability are key. FOR YOU, THIS MEANS SECURITY IN TERMS OF DELIVERY ANDAVAILABILITYOFSPAREPARTS. SIMULTANEOUSLY,WE ARE THUS ABLE TO PRODUCE TAILOR-MADE SOLUTIONS IN-HOUSE.
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Consumables
BASIS OF EVERY WORKFLOW
They are the essence of every workflow. Nothing works without the appropriate consumables. That's why we offer a whole range of high-quality consumables that provide more security, higher efficiency, and more convenience. We produce our tips in-house in our own production facilities, guaranteeing our idea of quality and a continuous availability of consumables. Tips are manufactured to the highest consistency and quality standards Automated cleanroom production Automatic digital image processing inspections Complete, documented traceability Production areas in accordance with ISO-1464444-1 (Class 8) Quality Management System in accordance with ISO 9001: 2015, ISO 13485: 2012, 21 CFR 820 (FDA Quality System Regulation) and EU In Vitro Diagnostics Directive Sterile CO-RE tips manufactured in accordance with ISO 11137-1, ISO 11137-2 and ISO 11137-3
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Specifications
Physical Dimensions Parameter Width without Multi-Probe Head with Multi-Probe Head
Processing Times Configuration
Microlab STARlet Microlab STAR
Task
Time(s)
Filling of one 96-well microplate with 100 µl sample (new tip for each sample)
320
1124 mm 1387 mm
1664 mm 1927 mm
8 Pipetting Channels
Aliquot reagent to a 96-well microplate (<90 µl per well)
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Height
903 mm
903 mm
Replication of one 96-well microplate: 100 µl, new tips, with cLLD on aspiration Reformatting of four 96 well microplates to one 384-well microplate: 50 µl, new tips, with cLLD on aspiration Replication of one 384-well micro- plate: 20 µl, new tips, with cLLD on aspiration Reformatting of 4 - 384 well microplates to one 1536-well microplate: 10 µl, new tips, with cLLD on aspiration
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Depth Manual Load Autoload
CO-RE 96 Probe Head
STARlet
781 mm 1011 mm
781 mm 1011 mm
140
Weight (8 Pipetting Channels) without Multi-Probe Head with Multi-Probe Head
135 kg 150 kg
145 kg 160 kg
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CO-RE 384 Probe Head
< 65 dBA < 46 dBA in standby mode
Noise Level
140
(according to EN 27779)
Deck Parameters Parameter
Depth: 30.75 in 781 mm
44.25 in 1124 mm
Microlab STARlet
Microlab STAR
Deck Capacity
30 Tracks (T)
54 Tracks (T)
Modal Precision
x-y-z positional accuracy of 0.1 mm
STAR
From 10 µL to 5000 µL For detailed information on the tip size gradiations, contact your local Hamilton representative
Tip Sizes
Ambient Conditions Parameter
Operation
Storage
Transportation
Temperature
+15º C - + 35º C
- 25º C - + 70º C
- 25º C - + 70º C
Relative Humidity
15%- 85% (non-condensing)
10%- 90% (non-condensing)
10%- 90% (non-condensing)
Overvoltage Category
II
II
II
Depth: 30.75 in 781 mm
65.5 in 1664 mm
Pollution Degree
2
2
2
Altitude
up to 2000 m/6561 ft. above sea level
Indoor use only
Housing Extension Multi-Probe Head
Slim Housing Extension left
Slim Housing Extension right
Electrical Data The maximum power consumption depends on the configuration of the instrument Maximum Power Consumption 600 VA Operating Data: Voltage:
Labware All SBS standard plate types up to 1536 wells and most commercially available tube types. Contact your local Hamilton representative for more information.
100/115 VAC / 230 VAC (± 10%)
Maximum height of labware on deck: 140 mm from deck surface
Frequency:
50/60 Hz
Delayed Action Fuse:
100/115 VAC: 6.3 A (T6.3AL250) 230 VAC: 3.15 A (T3.15AL250)
Carriers For all standard labware formats and according to customer requirements. Contact your local Hamilton representative for more information.
Maximum Power Consumption 1000 VA Operating Data: Voltage:
Depth: 30.75 in 781 mm
115 VAC / 230 VAC (± 10%)
Frequency:
50/60 Hz
Depth: 30.75 in 781 mm
Depth: 30.75 in 781 mm
Delayed Action Fuse:
115 VAC: 10 A (T10AL250) 230 VAC: 5 A (T5AL250)
10.35 in 263 mm
1.15 in 29 mm
1.15 in 29 mm
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Automating your IMAGINATION
We drive innovation to improve people's lives
HAMILTON ROBOTICS
We develop and produce state-of-the-art Liquid Handling Systems and laboratory automation technologies. Devote yourself to new ideas, trans- forming your ideas into reality. The entire product portfolio is characterized by maximum reliability, maximum efficiency, flexibility and user-friendliness. From production to service and support, the focus is always on your individual needs.
HAMILTON
Hamilton has stood for Life Sciences and Medical Technology since 1966. A visionary idea developed into a strong global presence. Our spirit has always remained the same: To research, develop and produce with passion, courage and curiosity. The desire to discover new, technological solutions, innovations, and benefit people is our mission too. We strive to set our goals high and continue to meet the measure of excellence.
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Benelux + 31 40 209 178 0
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Spain, Portugal +34 930 186 262
Italy +39 039 930 06 06
United States +1-775-858-3000
Brazil +55 11 95914 5000
To find a subsidiary or distributor in your area, please visit, www.hamiltoncompany.com/support.
United States +1-775-858-3000 United Kingdom, Ireland +44 121 272 92 80 Brazil +55 11 95914 5000 China +86 21 6164 6567
Denmark, Norway, Sweden, Finland +46 8410 27 373 France +33 184 008 420 Germany, Austria, Switzerland +49 89 248 804 804
Benelux +49 89 248 804 804 Italy +39 039 930 06 06 Japan +81 3 6435 6850 Spain, Portugal +34 930 186 262
Web: www.hamiltoncompany.com/robotics Email: infoservice@hamiltonrobotics.com
© 2022 Hamilton Company. All rights reserved.All trademarks are owned and/or registered by Hamilton Company in the U.S. and/or other countries. Lit. No. B-2201-01— 01/2022
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