Unpack your Prep with these simple steps!
Nice To Meet You
Read me to get started.
Welcome to the Microlab Prep
Now that your Prep has arrived, you are only a few short steps away from easily automating your workflows.
Before you get started, check out: hamiltoncompany.com/prephelp for the newest software version and other resources.
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SECTION 1: REQUIREMENTS
First, decide on a space in your lab to put the Prep. Ensure your space fits the following specifications:
The space must have a level surface with enough room for the Prep:
Width with Touchscreen: 22.5 in / 572 mm Width without Touchscreen: 20.9 in / 531 mm Depth with Touchscreen: 25.0 in / 636 mm Depth without Touchscreen: 24.3 in / 617 mm Height: 23.8 in / 604 mm Height: (Door Open) 31.9 in / 809 mm
Allocate additional space as needed so all parts of the Prep are easily accessible.
The area should be consistently well-lit, without shadows from windows (or other instruments) that would affect labware recognition.
The area must have an ambient temperature of 15–35°C (59–95°F) with a relative humidity of 15–85%, non-condensing.
The surface must be stable and able to support the Prep’s weight (91.5 lbs / 41.6 kg). Shaking and vibrations can negatively affect your results, especially for low-volume applications.
The space must have access to electrical power between 100 VAC to 240 VAC at 50 to 60 Hz.
Once you decide on a space, you can unbox and begin installing the Prep by following the instructions in this booklet.
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SECTION 2: UNBOXING
Double-check both of the ShockWatches and TiltWatch on the outside of the box labeled “Accessories inside.” If either ShockWatch has a red tab, or if the balls in either TiltWatch sit at 40° or higher, contact Hamilton support. 1
Remove the foam piece on top of the Prep. If the foam piece came off while lifting the box off the Prep, move on to Step 3. 2
Set aside all packing material to store later. If you need to repack your Prep for repair or return, you must use the same packing materials.
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SECTION 2: UNBOXING
Remove the power cable from the top of the packaging and set it aside. 3
Un-tape and unfold the flaps of the bag. 4
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SECTION 2: UNBOXING
Slide the next foam piece toward the front of the Prep, then lift it to remove it. 5
Remove the protective foam from the touchscreen. Move the flap on the plastic bag if needed. 6
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SECTION 2: UNBOXING
Remove the protective foam from under the door by pulling upward and away from the Prep. 7
Roll the plastic bag down over the Prep. 8
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SECTION 2: UNBOXING
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Lift the Prep out of the lower box and place it on the bench. Make sure the location meets the requirements on page 4 for best results. The handles are located on the lower edge of the left, right, and back sides of the Prep; the foam base has cutouts for the handles.
Open the door by pushing gently upwards on the bottom of the door. Remove the rubber band securing the waste bin to the waste block, then undo the twist-tie holding the waste bin down. Remove the black plastic waste bin and twist tie, which contains the Prep’s accessories.
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Remove the plastic wrap and make sure the following are present:
■ Hex Wrench Set P/N 6603180-01
■ Liquid Waste Bottle P/N 6600264-01
Do not lift or move the Prep with less than two people.
■ CO-RE Paddles P/N 186105 (if the Prep has 2 Independent Channels)
■ Teaching Needle P/N 182176
■ Surface Level P/N 56659-01
■ Waste Bag Wire Stand P/N 6603149-01
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■ Replacement Fuses P/N 1524-11
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SECTION 2: UNBOXING
Remove the Velcro securing the support foam labeled “C,” then remove the support foam. 11
Remove the two red arm locks from the rail at the back of the Prep. Rotate the red key counter clockwise to remove, then pinch the clamp to detach. 12
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SECTION 2: UNBOXING
Remove the thin foam strip labeled “B” at the back of the Prep. Pull the red tag up and to the right to remove it. 13
Move the pipetting arm to the right. Push gently on the front end of the arm to move it. 14
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SECTION 2: UNBOXING
Remove the channel support foam (labeled “A”). 15
Peel the plastic wrap off of both outside panels and inside of the left side panel. 16
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SECTION 3: PREPARING THE DECK
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Move the pipetting arm back to the center. Push gently on the front end of the arm to move it. 18
Remove the red channel locks from the pipetting arm, from front to back:
A. Rotate key counter clockwise and remove it.
C. Pull the channel to the front of the arm and repeat as necessary for each channel lock.
■ 2 Independent Channels: 3 locks
■ 8-Probe Head: 2 locks
■ 2 Independent Channels + 8-Probe Head: 4 locks
B. Pinch the clamp and remove it.
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SECTION 3: PREPARING THE DECK
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Install any devices you are integrating. Refer to the instructions included with your device. Continue to the next step if not applicable. 20
Z-lock Removal instructions
A. Locate Red channel locks. They are in back of each independent channel near the top of the instrument.
B. While holding the front of the channel with one
hand, Pull the lock toward the back of the instrument until it is removed. Repeat for both channels’ locks.
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SECTION 3: PREPARING THE DECK
Install the deck: 21
Slide the waste bin into place, to the right of the waste block. 22
A. Remove the deck and base plates from their packaging. If you have a device, the deck should have a cutout for it.
C. Install the base plates for each site. Press down on each plate to make sure it is secure.
B. Place the deck frame on the Prep. The sites numbered 4 and 8 should be at the front.
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SECTION 4: GETTING STARTED
Place the liquid waste bottle in its place at the back of the waste bin. Make sure to remove the cap. 23
Place the steel teaching needle in its slot on the waste block. If your accessory kit has CO-RE paddles, place them on their magnetic bracket on the back of the waste block. 24
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SECTION 4: GETTING STARTED
Unwrap the cord set aside in Step 3 and connect the Prep to a power outlet. 25
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Turn on the Prep and follow the instructions on-screen to begin setup. You will need a rack of tips for calibration during setup. To use 1,000 µL tips, make sure to remove the base plate from the site where they will be placed first. Removing the base plate is also required to use a tube pedestal or semi-skirted PCR plates.
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SECTION 4: GETTING STARTED
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If you have a barcode reader, connect it via USB after completing setup. The USB ports are on the left side of the Prep, near the bottom of the instrument.
You’re finished and ready to start PREP-ing!
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SECTION 5: CONSUMABLES
Hamilton offers a wide range of consumables that work with the Microlab Prep depending on the needs for your workflow.
To purchase consumables or look through our full product offering, visit: hamiltoncompany.com/consumables
CO-RE II Tips — 50 µL
CO-RE II Tips — 300 µL
Available Options
Part Number
Details
Available Options
Part Number
Details
50 μL Conductive Non-Sterile Filter Tip
235948
Case of 5,760 tips (Blister 5 x 96 tips per rack) Case of 5,760 tips (Blister 5 x 96 tips per rack) Case of 5,760 tips (Blister 5 x 96 tips per rack) Case of 5,760 tips (Blister 5 x 96 tips per rack)
300 μL Conductive Sterile Filter Tips 300 μL Conductive Sterile Non-Filter Tips
235938
Case of 5,760 tips (Blister 5 x 96 tips per rack) Case of 5,760 tips (Blister 5 x 96 tips per rack)
50 μL Conductive Non-Sterile Non-Filter Tips
235966
235937
50 μL Conductive Sterile Filter Tips
235979
300 μL Nested Conductive Non-Sterile Non-Filter Tips 300 μL Nested Conductive Sterile Non-Filter Tips
235950
Case of 11,520 tips (NTR 5 x 4 stack) Case of 11,520 tips (NTR 5 x 4 stack)
50 μL Conductive Sterile Non-Filter Tips
235978
235985
50 μL Nested Conductive Non-Sterile Non-Filter Tips 50 μL Nested Conductive Sterile Non-Filter Tips
235947
Case of 11,520 tips (NTR 5 x 4 stack) Case of 11,520 tips (NTR 5 x 4 stack)
CO-RE II Tips — 1,000 µL
235987
Available Options
Part Number
Details
1000 μL Conductive Non-Sterile Filter Tips
235905
Case of 3840 tips (Blister 5 x 96 tips per rack) Case of 3840 tips (Blister 5 x 96 tips per rack) Case of 3840 tips (Blister 5 x 96 tips per rack) Case of 3840 tips (Blister 5 x 96 tips per rack)
CO-RE II Tips — 300 µL
1000 μL Conductive Non-Sterile Non-Filter Tips
235904
Available Options
Part Number
Details
300 μL Conductive Non-Sterile Filter Tips
235903
Case of 5,760 tips (Blister 5 x 96 tips per rack) Case of 5,760 tips (Blister 5 x 96 tips per rack)
1000 μL Conductive Sterile Filter Tips 1000 μL Conductive Sterile Non-Filter Tips
235940
300 μL Conductive Non-Sterile Non-Filter Tips
235902
235939
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SECTION 5: CONSUMABLES
Microlab Prep Accessories and Consumables
Microlab Prep Accessories and Consumables
Available Options
Part Number
Details
Available Options
Part Number
Details
24 Position Small Tube Rack
6600409-01
24 position tube rack (Compatible tube size: 9.5–11.5 mm OD, 30–50mm H) 24 position tube rack (Compatible tube size: 10.5–16 mm OD, 75–125 mm H) 24 position tube rack for 15 mL conical tubes (14-16mm OD, 75-125mm H) and self-standing VTM-style tubes (14-16 mm OD, 75-105mm H)
Invitrogen 96 Position Post Magnetic Plate
94696-01
Compatible magnetic plate for bead based extractions Compatible magnetic plate for bead based extractions
Magnetic Well Ring Plate
OTP-TMOI-0051
24 Position Large Tube Rack
6600555-01
Alpaqua Magnum FLX Magnetic Plate Alpaqua Magnum EX Magnetic Plate
OTP-ALPQ-0008 Compatible magnetic plate for bead based extractions OTP-ALPQ-0007 Compatible magnetic plate for bead based extractions
15 mL Tube Rack
6605054-01
Alpaqua 96S Ring Magnetic Plate
OTP-A001322
Compatible magnetic plate for bead based extractions Adapter to improve cLLD performance for 384-well, full-skirt PCR plates Adapter to improve cLLD performance for 96-well, half-skirt PCR plate Adapter to improve cLLD performance for 96-well, full-skirt PCR plates
cLLD Adapter 384-Well PCR Plates
6607478-01
Framed Tip Rack
6600553-01
Rack for framed tips
Reagent Reservoir Rack
6600700-01
5 x 60 mL reagent rack
cLLD Adapter 96-Well, Half-Skirt PCR Plates
6607479-01
Handheld Barcode Scanner
6603432-01
1D handheld barcode scanner
Fume Hood Kit
6603189-01
Stand and cables for touch screen and enclosure removal
cLLD Adapter 96-Well, Full-Skirt PCR Plates
6607610-01
3 mm Hamilton Heater Shaker
6601885-01
Heats up to 105 °C and Shakes up to 2500 rpm Heats up to 105 °C and Shakes up to 2500 rpm
2 mm Hamilton Heater Shaker
6601885-02
CO-RE I Stop Disk Removal Tool
6603034-01
Tool for replacing stop discs
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SECTION 5: CONSUMABLES
SECTION 6: SUPPORT
Microlab Prep Accessories and Consumables Cont.
Hamilton is here for you! Browse our Online help center for troubleshooting information, file a support ticket, and download the latest software updates. Visit: hamiltoncompany.com/prephelp
Available Options
Part Number
Details
CO-RE I Stop Disk Kit (2 channel)
6603039-01
Replacement stop disks, o-rings and washers Replacement stop disks, o-rings and washers 2-Pack replacement o-rings (CO-RE II only) 10-Pack replacement o-rings (CO-RE II only)
CO-RE I Multi Probe Head Stop Disk Kit (8 channel)
6603039-02
CO-RE II O-Ring Kit (2-Pack) CO-RE II O-Ring Kit (10-Pack)
6607080-01
6607080-02
Silicone Oil
6603044-01
Lubrication for yearly maintenance
Verification Kit with Two Framed Tip Racks
6604125-01
Photometric and gravimetric volume verification kit; includes two framed tip racks Photometric and gravimetric volume verification kit
Verification Kit (Liquids and Labware)
6604125-02
Biohazard Waste Bags
6603183-01
Tip waste bags (50 per roll)
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+40 356 635 055
Headquarters / Manufacturing
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